write a regular expression to substitute string like c macro?

'hello world "hello"'.replace(regex,"HELLO") => 'HELLO world "hello"'

how to writ开发者_如何学运维e this regex which only substitute 'hello' which is not in quote?

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Assuming you're using Javascript:

'hello world "hello"'.replace(/($|[^"])hello(?!")/g,'$1HELLO');